Publications

2024

  1. Thalamocortical organoids enable in vitro modeling of 22q11.2 microdeletion associated with neuropsychiatric disorders. Cell Stem Cell. 2024 Mar 7;31(3):421-432.e8. Shin D, Kim CN, Ross J, Hennick KM, Wu SR, Paranjape N, Leonard R, Wang JC, Keefe MG, Pavlovic BJ, Donohue KC, Moreau C, Wigdor EM, Larson HH, Allen DE, Cadwell CR, Bhaduri A, Popova G, Bearden CE, Pollen AA, Jacquemont S, Sanders SJ, Haussler D, Wiita AP, Frost NA, Sohal VS, Nowakowski TJ. PMID: 38382530; PMCID: PMC10939828.

  2. Cell-Type Specificity of Mosaic Chromosome 1q Gain Resolved by snRNA-seq in a Case of Epilepsy With Hyaline Protoplasmic Astrocytopathy. Neurol Genet. 2024 Apr 3;10(2):e200142. Leng K, Cadwell CR, Devine WP, Tihan T, Qi Z, Singhal NS, Glenn OA, Kamiya S, Wiita AP, Berger AC, Shieh JT, Titus EW, Paredes MF, Upadhyay V. PMID: 38586598; PMCID: PMC10997208.

  3. Patch-seq: Multimodal Profiling of Single-Cell Morphology, Electrophysiology, and Gene Expression. Methods Mol Biol. 2024;2752:227-243. Cadwell CR, Tolias AS. PMID: 38194038.

  4. Prenatal AAV9-GFP administration in fetal lambs results in transduction of female germ cells and maternal exposure to virus. Mol Ther Methods Clin Dev. 2024 May 4;32(2):101263. Borges B, Varthaliti A, Schwab M, Clarke MT, Pivetti C, Gupta N, Cadwell CR, Guibinga G, Phillips S, Del Rio T, Ozsolak F, Imai-Leonard D, Kong L, Laird DJ, Herzeg A, Sumner CJ, MacKenzie TC. PMID: 38827250; PMCID: PMC11141462.

2023

  1. Dual ankyrinG and subpial autoantibodies in a man with well-controlled HIV infection with steroid-responsive meningoencephalitis: A case report. Front Neurol. 2023 Jan 23. Bartley CM, Ngo TT, Cadwell CR, Harroud A, Schubert RD, Alvarenga BD, Hawes IA, Zorn KC, Hunyh T, Teliska LH, Kung AF, Shah S, Gelfand JM, Chow FC, Rasband MN, Dubey D, Pittock SJ, DeRisi JL, Wilson MR, Pleasure SJ. PMID: 36756346.   

2022

  1. Fate mapping of neural stem cell niches reveals distinct origins of human cortical astrocytes. Science. 2022 Jun 24; 376(6600):1441-1446. Allen DE, Donohue KC, Cadwell CR, Shin D, Keefe MG, Sohal VS, Nowakowski TJ. PMID: 35587512; PMCID: PMC9233096.

  2. Targeted Next-Generation Sequencing Reveals Divergent Clonal Evolution in Components of Composite Pleomorphic Xanthoastrocytoma-Ganglioglioma. J Neuropathol Exp Neurol. 2022 Jun 15. Lucas CG, Davidson CJ, Alashari M, Putnam AR, Whipple NS, Bruggers CS, Mendez JS, Cheshier SH, Walker JB, Ramani B, Cadwell CR, Sullivan DV, Lu R, Mirchia K, Van Ziffle J, Devine P, Goldschmidt E, Hervey-Jumper SL, Gupta N, Oberheim Bush NA, Raleigh DR, Bollen A, Tihan T, Pekmezci M, Solomon DA, Phillips JJ, Perry A. PMID: 35703914.  

  3. Amyloid-β related angiitis presenting as eosinophilic meningitis: a case report. BMC Neurol. 2022 Mar 24; 22(1):116. Tanner JA, Richie MB, Cadwell CR, Eliaz A, Kim S, Haq Z, Rasool N, Shah MP, Guterman EL. PMID: 35331158; PMCID: PMC8944059.

2021

  1. A multimodal cell census and atlas of the mammalian primary motor cortex. Nature. 2021 10; 598(7879):86-102. BRAIN Initiative Cell Census Network (BICCN, 258 authors including Cadwell CR). PMID: 34616075; PMCID: PMC8494634.

  2. Phenotypic variation of transcriptomic cell types in mouse motor cortex. Nature. 2021 10; 598(7879):144-150. Scala F, Kobak D, Bernabucci M, Bernaerts Y, Cadwell CR, Castro JR, Hartmanis L, Jiang X, Laturnus S, Miranda E, Mulherkar S, Tan ZH, Yao Z, Zeng H, Sandberg R, Berens P, Tolias AS. PMID: 33184512; PMCID: PMC8113357.

  3. Preferentially Expressed Antigen in Melanoma (PRAME) Expression in Malignant, but Not Benign, Peripheral Nerve Sheath Tumors. J Neuropathol Exp Neurol. 2021 03 22; 80(4):384-386. Cadwell CR, Yuksek GE, Hirbe AC, Srihari D, LeBoit P, Dahiya S, Pekmezci M. PMID: 33212492.

  4. Loss of fidelity in scanned digital images compared to glass slides of brain tumors resected using cavitron ultrasonic surgical aspirator. Brain Pathol. 2021 07; 31(4):e12938. Cadwell CR, Bowman S, Laszik ZG, Pekmezci M. PMID: 33576118; PMCID: PMC8412125.

  5. Patch-seq: Past, Present, and Future. J Neurosci. 2021 02 03; 41(5):937-946. Lipovsek M, Bardy C, Cadwell CR, Hadley K, Kobak D, Tripathy SJ. PMID: 33431632; PMCID: PMC7880286.

2020

  1. Cell type composition and circuit organization of clonally related excitatory neurons in the juvenile mouse neocortex. Elife. 2020 03 05; 9. Cadwell CR, Scala F, Fahey PG, Kobak D, Mulherkar S, Sinz FH, Papadopoulos S, Tan ZH, Johnsson P, Hartmanis L, Li S, Cotton RJ, Tolias KF, Sandberg R, Berens P, Jiang X, Tolias AS. PMID: 32134385; PMCID: PMC7162653.

  2. Outer Radial Glia-like Cancer Stem Cells Contribute to Heterogeneity of Glioblastoma. Cell Stem Cell. 2020 01 02; 26(1):48-63.e6. Bhaduri A, Di Lullo E, Jung D, Müller S, Crouch EE, Espinosa CS, Ozawa T, Alvarado B, Spatazza J, Cadwell CR, Wilkins G, Velmeshev D, Liu SJ, Malatesta M, Andrews MG, Mostajo-Radji MA, Huang EJ, Nowakowski TJ, Lim DA, Diaz A, Raleigh DR, Kriegstein AR. PMID: 31901251; PMCID: PMC7029801.

  3. Comprehensive analysis of diverse low-grade neuroepithelial tumors with FGFR1 alterations reveals a distinct molecular signature of rosette-forming glioneuronal tumor. Acta Neuropathol Commun. 2020 08 28; 8(1):151. Lucas CG, Gupta R, Doo P, Lee JC, Cadwell CR, Ramani B, Hofmann JW, Sloan EA, Kleinschmidt-DeMasters BK, Lee HS, Wood MD, Grafe M, Born D, Vogel H, Salamat S, Puccetti D, Scharnhorst D, Samuel D, Cooney T, Cham E, Jin LW, Khatib Z, Maher O, Chamyan G, Brathwaite C, Bannykh S, Mueller S, Kline CN, Banerjee A, Reddy A, Taylor JW, Clarke JL, Oberheim Bush NA, Butowski N, Gupta N, Auguste KI, Sun PP, Roland JL, Raffel C, Aghi MK, Theodosopoulos P, Chang E, Hervey-Jumper S, Phillips JJ, Pekmezci M, Bollen AW, Tihan T, Chang S, Berger MS, Perry A, Solomon DA. PMID: 32859279; PMCID: PMC7456392.

  4. Development of renal cysts in a transplanted kidney. Am J Transplant. 2020 06; 20(6):1749-1751. Freise J, Cadwell C, Park M, Freise C. PMID: 32472640.

  5. Gliomas arising in the setting of Li-Fraumeni syndrome stratify into two molecular subgroups with divergent clinicopathologic features. Acta Neuropathol. 2020 05; 139(5):953-957. Sloan EA, Hilz S, Gupta R, Cadwell C, Ramani B, Hofmann J, Kline CN, Banerjee A, Reddy A, Oberheim Bush NA, Chang S, Braunstein S, Chang EF, Raffel C, Gupta N, Sun PP, Kim JYH, Moes G, Alva E, Li R, Bruggers CS, Alashari M, Wetmore C, Garg S, Dishop M, Van Ziffle J, Onodera C, Devine P, Grenert JP, Lee JC, Phillips JJ, Pekmezci M, Tihan T, Bollen AW, Berger MS, Costello JF, Perry A, Solomon DA. PMID: 32157385; PMCID: PMC7183424.

2019

  1. Development and Arealization of the Cerebral Cortex. Neuron. 2019 09 25; 103(6):980-1004. Cadwell CR, Bhaduri A, Mostajo-Radji MA, Keefe MG, Nowakowski TJ. PMID: 31557462.

  2. Layer 4 of mouse neocortex differs in cell types and circuit organization between sensory areas. Nat Commun. 2019 09 13; 10(1):4174. Scala F, Kobak D, Shan S, Bernaerts Y, Laturnus S, Cadwell CR, Hartmanis L, Froudarakis E, Castro JR, Tan ZH, Papadopoulos S, Patel SS, Sandberg R, Berens P, Jiang X, Tolias AS. PMID: 31519874; PMCID: PMC6744474.

  3. Author Correction: Layer 4 of mouse neocortex differs in cell types and circuit organization between sensory areas. Nat Commun. 2019 Nov 04; 10(1):5075. Scala F, Kobak D, Shan S, Bernaerts Y, Laturnus S, Cadwell CR, Hartmanis L, Froudarakis E, Castro JR, Tan ZH, Papadopoulos S, Patel SS, Sandberg R, Berens P, Jiang X, Tolias AS. PMID: 31685814; PMCID: PMC6828750.  

2018

  1. Management of Inverted Papilloma During Holmium Laser Enucleation of the Prostate. Urology. 2018 Jun; 116:e5-e6. Tzou DT, Cadwell C, Simko JP, Chi T, Stoller ML. PMID: 29545053.

2017

  1. Multimodal profiling of single-cell morphology, electrophysiology, and gene expression using Patch-seq. Nat Protoc. 2017 Dec; 12(12):2531-2553. Cadwell CR, Scala F, Li S, Livrizzi G, Shen S, Sandberg R, Jiang X, Tolias AS. PMID: 29189773; PMCID: PMC6422019.

  2. Q&A: using Patch-seq to profile single cells. BMC Biol. 2017 07 06; 15(1):58. Cadwell CR, Sandberg R, Jiang X, Tolias AS. PMID: 28679385; PMCID: PMC5499043.

2016

  1. Electrophysiological, transcriptomic and morphologic profiling of single neurons using Patch-seq. Nat Biotechnol. 2016 Feb; 34(2):199-203. Cadwell CR, Palasantza A, Jiang X, Berens P, Deng Q, Yilmaz M, Reimer J, Shen S, Bethge M, Tolias KF, Sandberg R, Tolias AS. PMID: 26689543; PMCID: PMC4840019.

  2. Response to Comment on "Principles of connectivity among morphologically defined cell types in adult neocortex". Science. 2016 09 09; 353(6304):1108. Jiang X, Shen S, Sinz F, Reimer J, Cadwell CR, Berens P, Ecker AS, Patel S, Denfield GH, Froudarakis E, Li S, Walker E, Tolias AS. PMID: 27609883.

2015

  1. Principles of connectivity among morphologically defined cell types in adult neocortex. Science. 2015 Nov 27; 350(6264):aac9462. Jiang X, Shen S, Cadwell CR, Berens P, Sinz F, Ecker AS, Patel S, Tolias AS. PMID: 26612957; PMCID: PMC4809866.

  2. Waking State: Rapid Variations Modulate Neural and Behavioral Responses. Neuron. 2015 Sep 23; 87(6):1143-1161. McGinley MJ, Vinck M, Reimer J, Batista-Brito R, Zagha E, Cadwell CR, Tolias AS, Cardin JA, McCormick DA. PMID: 26402600; PMCID: PMC4718218.

2014

  1. Pupil fluctuations track fast switching of cortical states during quiet wakefulness. Neuron. 2014 Oct 22; 84(2):355-62. Reimer J, Froudarakis E, Cadwell CR, Yatsenko D, Denfield GH, Tolias AS. PMID: 25374359; PMCID: PMC4323337.

  2. State dependence of noise correlations in macaque primary visual cortex. Neuron. 2014 Apr 02; 82(1):235-48. Ecker AS, Berens P, Cotton RJ, Subramaniyan M, Denfield GH, Cadwell CR, Smirnakis SM, Bethge M, Tolias AS. PMID: 24698278; PMCID: PMC3990250.

2012

  1. 5-HT2A receptor activation normalizes exaggerated fear behavior in p-chlorophenylalanine (PCPA)-treated rats. J Behav Brain Sci. 2012 Nov; 2(4):454-62. Hughes CR, Tran L, Keele NB. doi: 10.4236/jbbs.2012.24053.

2006

  1. Phenytoin normalizes exaggerated fear behavior in p-chlorophenylalanine (PCPA)-treated rats. Epilepsy Behav. 2006 Dec; 9(4):557-63. Hughes CR, Keele NB. PMID: 17045847; PMCID: PMC1764502.